Pages
Products

FPGT


Official Full Name
fucose-1-phosphate guanylyltransferase
Organism
Homo sapiens
Gene ID
8790
Background
L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose; the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene. [provided by RefSeq, Dec 2010]
Synonyms
GFPP

Cat.No. Product Name Price
SHH067547 shRNA set against Rat Fpgt(NM_199494.1) Inquiry
SHH067565 shRNA set against Mouse Fpgt(NM_029330.2) Inquiry
SHH296929 shRNA set against Human FPGT (NM_003838.3) Inquiry
SHH296933 shRNA set against Mouse FPGT (NM_029330.2) Inquiry
SHH296937 shRNA set against Rat FPGT (NM_199494.1) Inquiry
SHW003444 shRNA set against Chicken FPGT (NM_001204815) Inquiry
SHW008780 shRNA set against Danio rerio FPGT (NM_001020754) Inquiry
Cat.No. Product Name Price
CDFR015265 Rat Fpgt cDNA Clone(NM_199494.1) Inquiry
MiUTR1M-04791 FPGT miRNA 3'UTR clone Inquiry
MiUTR1R-01951 FPGT miRNA 3'UTR clone Inquiry
MiUTR3H-06116 FPGT miRNA 3'UTR clone Inquiry
CDCB164919 Chicken FPGT ORF Clone (NM_001204815) Inquiry
CDCB170255 Danio rerio FPGT ORF Clone (NM_001020754) Inquiry
CDCB182293 Rabbit FPGT ORF clone (NM_001204806.1) Inquiry
CDCL109415 Mouse FPGT ORF clone (NM_001199328.1) Inquiry
CDCL109417 Mouse FPGT ORF clone (NM_001199329.1) Inquiry
CDCL109419 Mouse Fpgt ORF clone (NM_029330.2) Inquiry
CDCR347897 Human FPGT ORF Clone(NM_001112808.2) Inquiry
CDCR382341 Rat Fpgt ORF Clone(NM_199494.1) Inquiry
CDCS409454 Human FPGT ORF Clone (BC032308) Inquiry
Quick Inquiry