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FKBP1B

Official Full Name
FKBP prolyl isomerase 1B
Organism
Homo sapiens
GeneID
2281
Background
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008]
Synonyms
OTK4; FKBP1L; PKBP1L; PPIase; FKBP12.6;

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