Pages
Products

FKBP1A


Official Full Name
FKBP prolyl isomerase 1A
Organism
Homo sapiens
Gene ID
2280
Background
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq, Sep 2008]
Synonyms
FKBP1; PKC12; PKCI2; FKBP12; PPIASE; FKBP-12; FKBP-1A

Cat.No. Product Name Price
SHH060419 shRNA set against Mouse Fkbp1a(NM_008019.2) Inquiry
SHH295202 shRNA set against Human FKBP1A (NM_000801.4) Inquiry
SHW004845 shRNA set against Chicken FKBP1A (NM_204330) Inquiry
Cat.No. Product Name Price
MiUTR1M-04723 FKBP1A miRNA 3'UTR clone Inquiry
MiUTR3H-02186 FKBP1A miRNA 3'UTR clone Inquiry
MiUTR3H-02187 FKBP1A miRNA 3'UTR clone Inquiry
CDCB166320 Chicken FKBP1A ORF Clone (NM_204330) Inquiry
CDCB180360 Rabbit FKBP1A ORF clone (NM_001171126.1) Inquiry
CDCR377850 Rat Fkbp1a ORF Clone(NM_013102.3) Inquiry
Quick Inquiry