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FGR


Official Full Name
FGR proto-oncogene, Src family tyrosine kinase
Organism
Homo sapiens
Gene ID
2268
Background
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Synonyms
SRC2; c-fgr; c-src2; p55-Fgr; p58-Fgr; p55c-fgr; p58c-fgr

Cat.No. Product Name Price
AD06240Z Human FGR adenoviral particles Inquiry
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SHH294793 shRNA set against Rat FGR (NM_024145.2) Inquiry
SHH059177 shRNA set against Human FGR(NM_001042729.1) Inquiry
SHH059213 shRNA set against Rat Fgr(NM_024145.2) Inquiry
SHH294785 shRNA set against Human FGR (NM_005248.2) Inquiry
SHH294789 shRNA set against Mouse FGR (NM_010208.4) Inquiry
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CDCG003900 Human FGR ORF clone(NM_005248.2) Inquiry
CDCR344732 Human FGR ORF Clone(NM_001042729.1) Inquiry
CDFH006875 Human FGR cDNA Clone(NM_001042729.1) Inquiry
CDFH006876 Human FGR cDNA Clone(NM_001042747.1) Inquiry
CDFR012275 Rat Fgr cDNA Clone(NM_024145.2) Inquiry
MiUTR1H-03652 FGR miRNA 3'UTR clone Inquiry
MiUTR1R-01906 FGR miRNA 3'UTR clone Inquiry
MiUTR3H-01614 FGR miRNA 3'UTR clone Inquiry
MiUTR3H-01615 FGR miRNA 3'UTR clone Inquiry
CDCB192161 Rabbit FGR ORF clone (XM_002716117.2) Inquiry
CDCG003901 Mouse FGR ORF clone(NM_010208.4) Inquiry
CDCR344736 Human FGR ORF Clone(NM_001042747.1) Inquiry
CDCR379352 Rat Fgr ORF Clone(NM_024145.2) Inquiry
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