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Fcgr3

Official Full Name
Fc receptor, IgG, low affinity III
Organism
Mus musculus
GeneID
14131
Background
Enables IgG binding activity and IgG receptor activity. Acts upstream of or within several processes, including antibody-dependent cellular cytotoxicity; phagocytosis; and positive regulation of hypersensitivity. Located in external side of plasma membrane. Is expressed in liver and spleen. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dengue disease (multiple); hematologic cancer (multiple); leukopenia (multiple); and malaria (multiple). Orthologous to human FCGR2A (Fc gamma receptor IIa). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Fcgr3; CD16;

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