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FXYD1


Official Full Name
FXYD domain containing ion transport regulator 1
Organism
Homo sapiens
Gene ID
5348
Background
This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity. Transcript variants with different 5' UTR sequences have been described in the literature. [provided by RefSeq, Jul 2008]
Synonyms
PLM

Cat.No. Product Name Price
SHH071273 shRNA set against Human FXYD1(NM_005031.3) Inquiry
SHH297921 shRNA set against Human FXYD1 (NM_005031.3) Inquiry
SHH297925 shRNA set against Mouse FXYD1 (NM_052991.4) Inquiry
SHW014016 shRNA set against Danio rerio FXYD1 (NM_001256212) Inquiry
Cat.No. Product Name Price
OE-PNDC000436 Human FXYD1 Nanodisc Inquiry
Cat.No. Product Name Price
CDFG003419 Human FXYD1 cDNA Clone(NM_021902.2) Inquiry
CDFH007201 Human FXYD1 cDNA Clone(NM_005031.3) Inquiry
MiUTR1H-03886 FXYD1 miRNA 3'UTR clone Inquiry
MiUTR3H-04908 FXYD1 miRNA 3'UTR clone Inquiry
CDCB160040 Human FXYD1 ORF clone (BC032800) Inquiry
CDCB175491 Danio rerio FXYD1 ORF Clone (NM_001256212) Inquiry
CDCG004699 Mouse FXYD1 ORF clone(NM_052992.3) Inquiry
CDCG004701 Mouse FXYD1 ORF clone(NM_194321.2) Inquiry
CDCL109901 Mouse Fxyd1 ORF clone (NM_019503.4) Inquiry
CDCR253973 Mouse Fxyd1 ORF Clone(NM_019503.4) Inquiry
CDCR264240 Mouse Fxyd1 ORF Clone(NM_052991.4) Inquiry
CDCR289468 Human FXYD1 ORF Clone(NM_005031.3) Inquiry
CDCR307169 Human FXYD1 ORF Clone(NM_021902.2) Inquiry
CDCR379803 Rat Fxyd1 ORF Clone(NM_031648.2) Inquiry
CDCS412066 Human FXYD1 ORF Clone (BC032800) Inquiry
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