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FHIT


Official Full Name
fragile histidine triad diadenosine triphosphatase
Organism
Homo sapiens
Gene ID
2272
Background
The protein encoded by this gene is a P1-P3-bis(5'-adenosyl) triphosphate hydrolase involved in purine metabolism. This gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. The encoded protein is also a tumor suppressor, as loss of its activity results in replication stress and DNA damage. [provided by RefSeq, Aug 2017]
Synonyms
FRA3B; AP3Aase

Cat.No. Product Name Price
SHW004104 shRNA set against Chicken FHIT (NM_001277802) Inquiry
SHH059321 shRNA set against Rat Fhit(NM_021774.1) Inquiry
SHH059339 shRNA set against Mouse Fhit(NM_010210.2) Inquiry
SHH294845 shRNA set against Mouse FHIT (NM_010210.2) Inquiry
SHH294849 shRNA set against Rat FHIT (NM_021774.1) Inquiry
SHW004105 shRNA set against Chicken FHIT (NM_001277803) Inquiry
SHW004106 shRNA set against Chicken FHIT (NM_001277804) Inquiry
SHW016889 shRNA set against Danio rerio FHIT (NM_200740) Inquiry
Cat.No. Product Name Price
CDFH006880 Human FHIT cDNA Clone(NM_001166243.1) Inquiry
CDFR011778 Rat Fhit cDNA Clone(NM_021774.1) Inquiry
MiUTR1M-04708 FHIT miRNA 3'UTR clone Inquiry
MiUTR1R-01908 FHIT miRNA 3'UTR clone Inquiry
MiUTR3H-03915 FHIT miRNA 3'UTR clone Inquiry
MiUTR3H-03916 FHIT miRNA 3'UTR clone Inquiry
CDCB158942 Human FHIT ORF clone (BC032336) Inquiry
CDCB165579 Chicken FHIT ORF Clone (NM_001277802) Inquiry
CDCB165580 Chicken FHIT ORF Clone (NM_001277803) Inquiry
CDCB165581 Chicken FHIT ORF Clone (NM_001277804) Inquiry
CDCB178364 Danio rerio FHIT ORF Clone (NM_200740) Inquiry
CDCB184143 Rabbit FHIT ORF clone (XM_002713411.2) Inquiry
CDCL108291 Human Fhit ORF clone (NM_010210.2) Inquiry
CDCR355252 Human FHIT ORF Clone(NM_001166243.1) Inquiry
CDCR378825 Rat Fhit ORF Clone(NM_021774.1) Inquiry
CDCS408827 Human FHIT ORF Clone (BC032336) Inquiry
Cat.No. Product Name Price
CC-523 FHIT Easy KO Kit Inquiry
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