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FGF8


Official Full Name
fibroblast growth factor 8
Organism
Homo sapiens
Gene ID
2253
Background
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008]
Synonyms
HH6; AIGF; KAL6; FGF-8; HBGF-8

Cat.No. Product Name Price
SHH294601 shRNA set against Human FGF8 (NM_006119.4) Inquiry
SHH294605 shRNA set against Mouse FGF8 (NM_010205.2) Inquiry
SHH294609 shRNA set against Rat FGF8 (NM_133286.1) Inquiry
SHW000939 shRNA set against Chicken FGF8 (NM_001012767) Inquiry
Cat.No. Product Name Price
CDCL108115 Mouse Fgf8 ORF clone (NM_001166361.1) Inquiry
CDFG020809 Mouse Fgf8 cDNA Clone(NM_001166363.1) Inquiry
CDFG020810 Mouse Fgf8 cDNA Clone(NM_001166362.1) Inquiry
CDFL004652 Mouse Fgf8 cDNA Clone(NM_010205.2) Inquiry
CDFR013962 Rat Fgf8 cDNA Clone(NM_133286.1) Inquiry
CDCB162414 Chicken FGF8 ORF Clone (NM_001012767) Inquiry
CDCB180313 Rabbit FGF8 ORF clone (XM_008270387.1) Inquiry
CDCL108113 Human FGF8 ORF clone (NM_001206389.1) Inquiry
CDCL108117 Human Fgf8 ORF clone (NM_001166362.1) Inquiry
CDCL108119 Human Fgf8 ORF clone (NM_001166363.1) Inquiry
CDCR248625 Mouse Fgf8 ORF Clone(NM_010205.2) Inquiry
CDCR313521 Human FGF8 ORF Clone(NM_033164.3) Inquiry
CDCR380996 Rat Fgf8 ORF Clone(NM_133286.1) Inquiry
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