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FGD1


Official Full Name
FYVE, RhoGEF and PH domain containing 1
Organism
Homo sapiens
Gene ID
2245
Background
This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of the faciogenital dysplasia in Aarskog-Scott syndrome and a syndromatic form of X-linked cognitive disability. [provided by RefSeq, Jul 2017]
Synonyms
AAS; FGDY; MRXS16; ZFYVE3

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SHH056423 shRNA set against Mouse Fgd1(NM_008001.3) Inquiry
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Cat.No. Product Name Price
CDFG022330 Mouse Fgd1 cDNA Clone(BC011462) Inquiry
CDFH006810 Human FGD1 cDNA Clone(NM_004463.2) Inquiry
CDFR004572 Rat Fgd1 cDNA Clone(NM_001037546.1) Inquiry
MiUTR1H-03620 FGD1 miRNA 3'UTR clone Inquiry
MiUTR1M-04676 FGD1 miRNA 3'UTR clone Inquiry
MiUTR1R-01876 FGD1 miRNA 3'UTR clone Inquiry
CDCB187956 Rabbit FGD1 ORF clone (XM_008272662.1) Inquiry
CDCL107935 Mouse FGD1 ORF clone (NM_004463.2) Inquiry
CDCL107937 Mouse Fgd1 ORF clone (NM_008001.3) Inquiry
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