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FGB


Official Full Name
fibrinogen beta chain
Organism
Homo sapiens
Gene ID
2244
Background
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Fibrinogen serves key roles in hemostasis and antimicrobial host defense. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. [provided by RefSeq, Aug 2020]
Synonyms
HEL-S-78p

Cat.No. Product Name Price
SHH294281 shRNA set against Mouse FGB (NM_181849.2) Inquiry
SHH056387 shRNA set against Mouse Fgb(NM_181849.2) Inquiry
SHH056405 shRNA set against Rat Fgb(NM_020071.2) Inquiry
SHH294277 shRNA set against Human FGB (NM_005141.4) Inquiry
SHH294286 shRNA set against Rat FGB (NM_020071.2) Inquiry
SHW002951 shRNA set against Chicken FGB (NM_001167683) Inquiry
SHW017928 shRNA set against Danio rerio FGB (NM_212774) Inquiry
Cat.No. Product Name Price
CDCS409126 Human FGB ORF Clone (BC106760) Inquiry
CDFH006807 Human FGB cDNA Clone(NM_001184741.1) Inquiry
CDFR011633 Rat Fgb cDNA Clone(NM_020071.2) Inquiry
MiUTR1M-04675 FGB miRNA 3'UTR clone Inquiry
MiUTR1R-01875 FGB miRNA 3'UTR clone Inquiry
MiUTR3H-00792 FGB miRNA 3'UTR clone Inquiry
CDCB157875 Human FGB ORF clone (BC106760) Inquiry
CDCB164426 Chicken FGB ORF Clone (NM_001167683) Inquiry
CDCB179403 Danio rerio FGB ORF Clone (NM_212774) Inquiry
CDCB187066 Rabbit FGB ORF clone (XM_002716890.2) Inquiry
CDCL107929 Mouse FGB ORF clone (NM_001184741.1) Inquiry
CDCL107931 Human Fgb ORF clone (NM_181849.2) Inquiry
CDCR378680 Rat Fgb ORF Clone(NM_020071.2) Inquiry
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