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FERMT2

Official Full Name
FERM domain containing kindlin 2
Organism
Homo sapiens
GeneID
10979
Background
Enables several functions, including phosphatidylinositol-3,4,5-trisphosphate binding activity; protein serine/threonine kinase binding activity; and type I transforming growth factor beta receptor binding activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of cellular component biogenesis; and positive regulation of intracellular signal transduction. Acts upstream of or within cell adhesion and protein localization to cell junction. Located in several cellular components, including adherens junction; cytoplasmic side of plasma membrane; and focal adhesion. Biomarker of acute myeloid leukemia. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
MIG2; KIND2; mig-2; UNC112; PLEKHC1; UNC112B;

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