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FDPS


Official Full Name
farnesyl diphosphate synthase
Organism
Homo sapiens
Gene ID
2224
Background
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008]
Synonyms
FPS; FPPS; POROK9

Cat.No. Product Name Price
SHH055307 shRNA set against Rat Fdps(NM_031840.1) Inquiry
SHH293933 shRNA set against Mouse FDPS (NM_134469.4) Inquiry
SHH293937 shRNA set against Rat FDPS (NM_031840.1) Inquiry
SHW008995 shRNA set against Danio rerio FDPS (NM_001025471) Inquiry
Cat.No. Product Name Price
MiUTR3H-00777 FDPS miRNA 3'UTR clone Inquiry
MiUTR3H-00775 FDPS miRNA 3'UTR clone Inquiry
MiUTR1R-01864 FDPS miRNA 3'UTR clone Inquiry
CDFR012969 Rat Fdps cDNA Clone(NM_031840.1) Inquiry
CDFH006767 Human FDPS cDNA Clone(NM_001135821.1) Inquiry
CDFH006766 Human FDPS cDNA Clone(NM_001135822.1) Inquiry
MiUTR3H-00776 FDPS miRNA 3'UTR clone Inquiry
CDCS408135 Human FDPS ORF Clone (BC010004) Inquiry
CDCR379983 Rat Fdps ORF Clone(NM_031840.1) Inquiry
CDCL107763 Human FDPS ORF clone (NM_001135822.1) Inquiry
CDCG003667 Mouse FDPS ORF clone(NM_134469.4) Inquiry
CDCG003665 Mouse FDPS ORF clone(NM_001253751.1) Inquiry
CDCB181554 Rabbit FDPS ORF clone (XM_008264341.1) Inquiry
CDCB170470 Danio rerio FDPS ORF Clone (NM_001025471) Inquiry
CDCB159987 Human FDPS ORF clone (BC010004) Inquiry
CDCR350516 Human FDPS ORF Clone(NM_001135821.1) Inquiry
CDCB157112 Mouse FDPS ORF clone (AK088601.1) Inquiry
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