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FBXW10


Official Full Name
F-box and WD repeat domain containing 10
Organism
Homo sapiens
Gene ID
10517
Background
Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Synonyms
HREP; Fbw10; SM25H2; SM2SH2

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SHH293457 shRNA set against Mouse FBXW10 (NM_001033669.2) Inquiry
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