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FBXO8


Official Full Name
F-box protein 8
Organism
Homo sapiens
Gene ID
26269
Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity. [provided by RefSeq, Jul 2008]
Synonyms
FBS; DC10; FBX8

Cat.No. Product Name Price
SHH053237 shRNA set against Mouse Fbxo8(NM_015791.3) Inquiry
SHH053253 shRNA set against Human FBXO8(NM_012180.2) Inquiry
SHH053271 shRNA set against Rat Fbxo8(NM_001012050.1) Inquiry
SHH293429 shRNA set against Human FBXO8 (NM_012180.2) Inquiry
SHH293433 shRNA set against Mouse FBXO8 (NM_015791.3) Inquiry
SHH293437 shRNA set against Rat FBXO8 (NM_001012050.1) Inquiry
SHW000528 shRNA set against Chicken FBXO8 (NM_001006446) Inquiry
SHW009632 shRNA set against Danio rerio FBXO8 (NM_001040307) Inquiry
Cat.No. Product Name Price
CDFH006702 Human FBXO8 cDNA Clone(NM_012180.2) Inquiry
CDFH006703 Human FBXO8 cDNA Clone(NM_012180.2) Inquiry
CDFR002478 Rat Fbxo8 cDNA Clone(NM_001012050.1) Inquiry
MiUTR1H-03568 FBXO8 miRNA 3'UTR clone Inquiry
MiUTR1M-04633 FBXO8 miRNA 3'UTR clone Inquiry
MiUTR1R-01853 FBXO8 miRNA 3'UTR clone Inquiry
CDCB162003 Chicken FBXO8 ORF Clone (NM_001006446) Inquiry
CDCB171107 Danio rerio FBXO8 ORF Clone (NM_001040307) Inquiry
CDCB183018 Rabbit FBXO8 ORF clone (XM_008249924.1) Inquiry
CDCR295548 Human FBXO8 ORF Clone(NM_012180.2) Inquiry
CDCR369525 Rat Fbxo8 ORF Clone(NM_001012050.1) Inquiry
CDCS413235 Human FBXO8 ORF Clone (BC014679) Inquiry
CDCS413236 Human FBXO8 ORF Clone (BC040456) Inquiry
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