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fbn2b


Official Full Name
fibrillin 2b
Organism
Danio rerio
Gene ID
571786
Background
Predicted to be an extracellular matrix structural constituent. Acts upstream of or within several processes, including circulatory system development; notochord morphogenesis; and regulation of cell proliferation involved in heart valve morphogenesis. Predicted to be located in extracellular region and microfibril. Predicted to be active in extracellular matrix. Is expressed in several structures, including epidermis; hypoblast; hypochord; immature eye; and paraxial mesoderm. Human ortholog(s) of this gene implicated in congenital contractural arachnodactyly and scoliosis. Orthologous to several human genes including FBN2 (fibrillin 2). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
fbn2

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