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Fam57B

Official Full Name
TLC domain containing 3B
Organism
Mus musculus
GeneID
68952
Background
Enables sphingosine N-acyltransferase activity. Acts upstream of or within ceramide biosynthetic process and negative regulation of fat cell differentiation. Predicted to be located in Golgi membrane and endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Is expressed in nervous system and neural retina. Used to study cone-rod dystrophy. Human ortholog(s) of this gene implicated in cone-rod dystrophy 22. Orthologous to human TLCD3B (TLC domain containing 3B). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Tlcd3b; Fam57b; 1500016O10Rik; A330104J06Rik;

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