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EPS15

Official Full Name
epidermal growth factor receptor pathway substrate 15
Organism
Homo sapiens
GeneID
2060
Background
This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2009]
Synonyms
AF1P; AF-1P; MLLT5;

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