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EIF4E2

Official Full Name
eukaryotic translation initiation factor 4E family member 2
Organism
Homo sapiens
GeneID
9470
Background
Enables RNA 7-methylguanosine cap binding activity; mRNA cap binding activity; and ubiquitin protein ligase binding activity. Involved in negative regulation of translational initiation; negative regulation of type I interferon-mediated signaling pathway; and rescue of stalled ribosome. Acts upstream of with a positive effect on miRNA-mediated gene silencing by inhibition of translation. Acts upstream of or within negative regulation of translation. Located in P-body. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
4EHP; IF4e; 4E-LP; h4EHP; EIF4EL3;

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