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EGLN3

Official Full Name
egl-9 family hypoxia inducible factor 3
Organism
Homo sapiens
GeneID
112399
Background
Enables peptidyl-proline 4-dioxygenase activity. Involved in several processes, including positive regulation of cysteine-type endopeptidase activity; protein hydroxylation; and response to hypoxia. Located in cytosol and nucleus. Implicated in renal cell carcinoma. Biomarker of clear cell renal cell carcinoma. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
PHD3; HIFPH3; HIFP4H3;

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