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ERCC3

Official Full Name
ERCC excision repair 3, TFIIH core complex helicase subunit
Organism
Homo sapiens
GeneID
2071
Background
This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Synonyms
XPB; BTF2; Ssl2; TTD2; GTF2H; RAD25; TFIIH;

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