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erbb3a


Official Full Name
erb-b2 receptor tyrosine kinase 3a
Organism
Danio rerio
Gene ID
386635
Background
Predicted to enable neuregulin binding activity and neuregulin receptor activity. Predicted to be involved in several processes, including epidermal growth factor receptor signaling pathway; positive regulation of MAPK cascade; and positive regulation of epithelial cell proliferation. Predicted to act upstream of or within cell surface receptor protein tyrosine kinase signaling pathway and protein phosphorylation. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in basal plasma membrane. Is expressed in epidermis; fin; glial cell; and heart. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome 2; lung adenocarcinoma; lung non-small cell carcinoma; and neuronal intestinal dysplasia type A. Orthologous to human ERBB3 (erb-b2 receptor tyrosine kinase 3). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
ERBB; erbb3; v-erb-b; im:7148890; si:dz150i12.1

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