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EPHB2


Official Full Name
EPH receptor B2
Organism
Homo sapiens
Gene ID
2048
Background
This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
Synonyms
DRT; EK5; ERK; CAPB; Hek5; PCBC; EPHT3; Tyro5; BDPLT22

Cat.No. Product Name Price
SHH036281 shRNA set against Human EPHB2(NM_004442.6) Inquiry
SHH036299 shRNA set against Human EPHB2(NM_017449.3) Inquiry
SHH036317 shRNA set against Mouse Ephb2(NM_010142.2) Inquiry
SHH286453 shRNA set against Human Ephb2 (NM_004442.6) Inquiry
SHH286457 shRNA set against Mouse Ephb2 (NM_010142.2) Inquiry
SHH286461 shRNA set against Rat Ephb2 (NM_001127319.1) Inquiry
SHW006038 shRNA set against Chicken EPHB2 (NM_206951) Inquiry
Cat.No. Product Name Price
CDCL184074 Human EphB2 ORF clone(NM_004442.6) Inquiry
CDFR009525 Rat Ephb2 cDNA Clone(NM_001127319.1) Inquiry
MiUTR1H-03263 EPHB2 miRNA 3'UTR clone Inquiry
MiUTR1H-03264 EPHB2 miRNA 3'UTR clone Inquiry
MiUTR1M-04434 EPHB2 miRNA 3'UTR clone Inquiry
CDCB167513 Chicken EPHB2 ORF Clone (NM_206951) Inquiry
CDCB182369 Rabbit EPHB2 ORF clone (XM_008265706.1) Inquiry
CDCL184075 Rat EPHB2 ORF clone(NM_001127319.1) Inquiry
CDCR060808 Human EPHB2 ORF clone (NM_017449.3) Inquiry
CDCR060814 Mouse Ephb2 ORF clone (NM_010142.2) Inquiry
CDCS411785 Human EPHB2 ORF Clone (BC067861) Inquiry
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