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ELN


Official Full Name
elastin
Organism
Homo sapiens
Gene ID
2006
Background
This gene encodes a protein that is one of the two components of elastic fibers. Elastic fibers comprise part of the extracellular matrix and confer elasticity to organs and tissues including the heart, skin, lungs, ligaments, and blood vessels. The encoded protein is rich in hydrophobic amino acids such as glycine and proline, which form mobile hydrophobic regions bounded by crosslinks between lysine residues. Degradation products of the encoded protein, known as elastin-derived peptides or elastokines, bind the elastin receptor complex and other receptors and stimulate migration and proliferation of monocytes and skin fibroblasts. Elastokines can also contribute to cancer progression. Deletions and mutations in this gene are associated with supravalvular aortic stenosis (SVAS) and autosomal dominant cutis laxa. [provided by RefSeq, Aug 2017]
Synonyms
WS; WBS; SVAS; ADCL1

Cat.No. Product Name Price
SHG210169 shRNA set against Mouse Eln(NM_007925.3) Inquiry
SHH031553 shRNA set against Human ELN(NM_001081752.1) Inquiry
SHG210151 shRNA set against Human ELN(NM_001081753.1) Inquiry
SHG210173 shRNA set against Human ELN(NM_000501.2) Inquiry
SHG210205 shRNA set against Rat Eln(NM_012722.1) Inquiry
SHG210223 shRNA set against Human ELN(NM_001081754.1) Inquiry
SHH031529 shRNA set against Human ELN(NM_001081752.1) Inquiry
SHH031535 shRNA set against Human ELN(NM_001081755.1) Inquiry
SHH285221 shRNA set against Human ELN (NM_000501.2) Inquiry
SHH285225 shRNA set against Mouse ELN (NM_007925.3) Inquiry
SHW004473 shRNA set against Chicken ELN (NM_001293107) Inquiry
Cat.No. Product Name Price
CDFH005865 Human ELN cDNA Clone(NM_001081752.1) Inquiry
MiUTR1H-03203 ELN miRNA 3'UTR clone Inquiry
MiUTR1H-03202 ELN miRNA 3'UTR clone Inquiry
MiUTR1H-03201 ELN miRNA 3'UTR clone Inquiry
MiUTR1H-03200 ELN miRNA 3'UTR clone Inquiry
CDFR010535 Rat Eln cDNA Clone(NM_012722.1) Inquiry
CDFH005868 Human ELN cDNA Clone(NM_001081755.1) Inquiry
CDFH005867 Human ELN cDNA Clone(NM_001081754.1) Inquiry
CDFH005866 Human ELN cDNA Clone(NM_001081753.1) Inquiry
MiUTR1H-03204 ELN miRNA 3'UTR clone Inquiry
MiUTR1M-04365 ELN miRNA 3'UTR clone Inquiry
CDCR059958 Human ELN ORF clone (NM_001081753.1) Inquiry
CDCR059956 Human ELN ORF clone (NM_001081752.1) Inquiry
CDCR059954 Human ELN ORF clone (NM_000501.2) Inquiry
CDCR377582 Rat Eln ORF Clone(NM_012722.1) Inquiry
CDCR244560 Mouse Eln ORF Clone(NM_007925.3) Inquiry
CDCR059962 Human ELN ORF clone (NM_001081755.1) Inquiry
CDCR059960 Human ELN ORF clone (NM_001081754.1) Inquiry
CDCB191167 Rabbit ELN ORF clone (XM_008249087.1) Inquiry
CDCS405701 Human ELN ORF Clone (BC065566) Inquiry
CDCB165948 Chicken ELN ORF Clone (NM_001293107) Inquiry
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