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EIF4G3

Official Full Name
eukaryotic translation initiation factor 4 gamma 3
Organism
Homo sapiens
GeneID
8672
Background
The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p. [provided by RefSeq, May 2016]
Synonyms
eIF4G 3; eIF4GII; eIF-4G 3;

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