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EIF3S7

Official Full Name
eukaryotic translation initiation factor 3 subunit D
Organism
Homo sapiens
GeneID
8664
Background
Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex. [provided by RefSeq, Jul 2008]
Synonyms
EIF3D; EIF3S7; eIF3-p66; eIF3-zeta;

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