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EIF2B3

Official Full Name
eukaryotic translation initiation factor 2B subunit gamma
Organism
Homo sapiens
GeneID
8891
Background
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Synonyms
VWM3; EIF-2B; EIF2Bgamma;

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