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EIF2AK3


Official Full Name
eukaryotic translation initiation factor 2 alpha kinase 3
Organism
Homo sapiens
Gene ID
9451
Background
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015]
Synonyms
PEK; WRS; PERK

Cat.No. Product Name Price
SHH028469 shRNA set against Mouse Eif2ak3(NM_010121.2) Inquiry
SHH284229 shRNA set against Human Eif2ak3 (NM_004836.5) Inquiry
SHH284233 shRNA set against Mouse Eif2ak3 (NM_010121.2) Inquiry
SHH284237 shRNA set against Rat Eif2ak3 (NM_031599.2) Inquiry
Cat.No. Product Name Price
MiUTR1M-04309 EIF2AK3 miRNA 3'UTR clone Inquiry
MiUTR3H-06451 EIF2AK3 miRNA 3'UTR clone Inquiry
SKO0447 EIF2AK3 Validated sgRNA vector Inquiry
CDCB185026 Rabbit EIF2AK3 ORF clone (XM_008254145.1) Inquiry
CDCR059402 Mouse Eif2ak3 ORF clone (NM_010121.2) Inquiry
CDCR379618 Rat Eif2ak3 ORF Clone(NM_031599.2) Inquiry
CDCS411979 Human EIF2AK3 ORF Clone (BC126354) Inquiry
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