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EHHADH

Official Full Name
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
Organism
Homo sapiens
GeneID
1962
Background
The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Synonyms
LBP; ECHD; LBFP; MFE1; PBFE; FRTS3; L-PBE;

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