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EDARADD


Official Full Name
EDAR associated via death domain
Organism
Homo sapiens
Gene ID
128178
Background
This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Synonyms
CR; ED3; EDA3; ECTD11A; ECTD11B

Cat.No. Product Name Price
SHH023375 shRNA set against Human EDARADD(NM_145861.2) Inquiry
SHH023411 shRNA set against Human EDARADD(NM_080738.3) Inquiry
SHH283073 shRNA set against Human EDARADD (NM_080738.3) Inquiry
SHH283077 shRNA set against Mouse EDARADD (NM_133643.4) Inquiry
SHW000837 shRNA set against Chicken EDARADD (NM_001012405) Inquiry
Cat.No. Product Name Price
MiUTR1H-03101 EDARADD miRNA 3'UTR clone Inquiry
MiUTR1H-03102 EDARADD miRNA 3'UTR clone Inquiry
CDCB157645 Human EDARADD ORF clone (BC128082) Inquiry
CDCB162312 Chicken EDARADD ORF Clone (NM_001012405) Inquiry
CDCB181444 Rabbit EDARADD ORF clone (XM_008268206.1) Inquiry
CDCH016647 Mouse EDARADD ORF clone(NM_133643.4) Inquiry
CDCR058570 Human EDARADD ORF clone (NM_145861.2) Inquiry
CDCS418484 Human EDARADD ORF Clone (BC128082) Inquiry
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