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ECSCR

Official Full Name
endothelial cell surface expressed chemotaxis and apoptosis regulator
Organism
Homo sapiens
GeneID
641700
Background
The protein encoded by this gene is primarily found in endothelial cells and blood vessels, where it is involved in cell shape changes and EGF-induced cell migration. It can enhance the activation of vascular endothelial growth factor receptor-2/kinase insert domain receptor and also promote the proteolysis of internalized kinase insert domain receptor. This gene may play a role in angiogenesis-related diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Synonyms
ARIA; ECSM2;

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