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E4F1


Official Full Name
E4F transcription factor 1
Organism
Homo sapiens
Gene ID
1877
Background
The zinc finger protein encoded by this gene is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. A 50-kDa amino-terminal product is generated from the full-length protein through proteolytic cleavage. The protein is differentially regulated by E1A-induced phosphorylation. The full-length gene product represses transcription from the E4 promoter in the absence of E1A, while the 50-kDa form acts as a transcriptional activator in its presence. Alternative splicing results in multiple transcripts encoding different proteins. [provided by RefSeq, Jan 2014]
Synonyms
E4F

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SHH022241 shRNA set against Human E4F1(NM_004424.3) Inquiry
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Cat.No. Product Name Price
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