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DYX1C1

Official Full Name
dynein axonemal assembly factor 4
Organism
Homo sapiens
GeneID
161582
Background
This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. An homologous protein in rat has been shown to function in neuronal migration in the developing neocortex. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream cell cycle progression 1 (CCPG1) gene. [provided by RefSeq, Mar 2011]
Synonyms
DNAAF4; RD; DYX1; EKN1; pf23; DYXC1; CILD25; DYX1C1;

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