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DUOX2

Official Full Name
dual oxidase 2
Organism
Homo sapiens
GeneID
50506
Background
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. [provided by RefSeq, Jul 2008]
Synonyms
TDH6; LNOX2; THOX2; NOXEF2; P138-TOX;

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