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DSG4

Official Full Name
desmoglein 4
Organism
Homo sapiens
GeneID
147409
Background
This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth. [provided by RefSeq, May 2016]
Synonyms
LAH; HYPT6; CDGF13; CDHF13;

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