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DRAP1


Official Full Name
DR1 associated protein 1
Organism
Homo sapiens
Gene ID
10589
Background
Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008]
Synonyms
NC2-alpha

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SHH015545 shRNA set against Mouse Drap1(NM_024176.1) Inquiry
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SHH280997 shRNA set against Rat DRAP1 (NM_001077668.2) Inquiry
SHW017475 shRNA set against Danio rerio DRAP1 (NM_205541) Inquiry
Cat.No. Product Name Price
CDCB158835 Human DRAP1 ORF clone (BC010025) Inquiry
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CDCB183707 Rabbit DRAP1 ORF clone (XM_002709241.2) Inquiry
CDCR057300 Mouse Drap1 ORF clone (NM_024176.1) Inquiry
CDCR372077 Rat Drap1 ORF Clone(NM_001077668.2) Inquiry
CDCS412743 Human DRAP1 ORF Clone (BC010025) Inquiry
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