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Dfna5h


Official Full Name
gasdermin E
Organism
Mus musculus
Gene ID
54722
Background
Enables cardiolipin binding activity. Involved in cellular response to virus and pyroptotic inflammatory response. Acts upstream of or within inner ear auditory receptor cell differentiation. Located in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 5 and sensorineural hearing loss. Orthologous to human GSDME (gasdermin E). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Gsdme; Dfna5; Fin15; Dfna5h; EG14210; 2310037D07Rik; 4932441K13Rik

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