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DEFA3


Official Full Name
defensin alpha 3
Organism
Homo sapiens
Gene ID
1668
Background
Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 1 by only one amino acid. This gene and the gene encoding defensin, alpha 1 are both subject to copy number variation. [provided by RefSeq, Oct 2014]
Synonyms
HP3; DEF3; HNP3; HP-3; HNP-3

Cat.No. Product Name Price
CDFG022156 Mouse Defa3 cDNA Clone(NM_007850.2) Inquiry
MiUTR3H-06886 DEFA3 miRNA 3'UTR clone Inquiry
CDCB158422 Human DEFA3 ORF clone (BC027917) Inquiry
CDCR244418 Mouse Defa3 ORF Clone(NM_007850.2) Inquiry
CDCS412147 Human DEFA3 ORF Clone (BC027917) Inquiry
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