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DCAF6

Official Full Name
DDB1 and CUL4 associated factor 6
Organism
Homo sapiens
GeneID
55827
Background
The protein encoded by this gene is a ligand-dependent coactivator of nuclear receptors, including nuclear receptor subfamily 3 group C member 1 (NR3C1), glucocorticoid receptor (GR), and androgen receptor (AR). The encoded protein and DNA damage binding protein 2 (DDB2) may act as tumor promoters and tumor suppressors, respectively, by regulating the level of androgen receptor in prostate tissues. In addition, this protein can act with glucocorticoid receptor to promote human papillomavirus gene expression. [provided by RefSeq, Mar 2017]
Synonyms
NRIP; ARCAP; IQWD1; PC326; MSTP055; 1200006M05Rik;

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