Pages
Products

DUX2


Official Full Name
double homeobox 4 like 8 (pseudogene)
Organism
Homo sapiens
Gene ID
26583
Background
This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length and a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. There is no evidence for transcription of the gene at this locus though RT-PCR and in vitro expression experiments indicate that a telomeric paralog of this gene is transcribed in some haplotypes. Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). [provided by RefSeq, Jun 2014]
Synonyms
DUX2

Cat.No. Product Name Price
SHH281977 shRNA set against Human DUX2 (NM_012147.3) Inquiry
Cat.No. Product Name Price
MiUTR4H-TG11102 DUX2 miRNA 3'UTR clone Inquiry
CDCR295481 Human DUX2 ORF Clone(NM_012147.3) Inquiry
Quick Inquiry