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DUSP9


Official Full Name
dual specificity phosphatase 9
Organism
Homo sapiens
Gene ID
1852
Background
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Synonyms
MKP4; MKP-4

Cat.No. Product Name Price
SHH019577 shRNA set against Rat Dusp9(NM_001037973.1) Inquiry
SHH019595 shRNA set against Human DUSP9(NM_001395.2) Inquiry
SHH019559 shRNA set against Mouse Dusp9(NM_029352.3) Inquiry
SHH281937 shRNA set against Human DUSP9 (NM_001395.2) Inquiry
SHH281941 shRNA set against Mouse DUSP9 (NM_029352.3) Inquiry
SHH281945 shRNA set against Rat DUSP9 (NM_001037973.1) Inquiry
Cat.No. Product Name Price
CDFR004635 Rat Dusp9 cDNA Clone(NM_001037973.1) Inquiry
MiUTR1H-03044 DUSP9 miRNA 3'UTR clone Inquiry
MiUTR1M-04068 DUSP9 miRNA 3'UTR clone Inquiry
MiUTR1R-01616 DUSP9 miRNA 3'UTR clone Inquiry
CDCB186204 Rabbit DUSP9 ORF clone (XM_002722630.2) Inquiry
CDCH386089 Human DUSP9 ORF clone(NM_001395.2) Inquiry
CDCR057826 Mouse Dusp9 ORF clone (NM_029352.3) Inquiry
CDCR371666 Rat Dusp9 ORF Clone(NM_001037973.1) Inquiry
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