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DUSP7


Official Full Name
dual specificity phosphatase 7
Organism
Homo sapiens
Gene ID
1849
Background
Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]
Synonyms
MKPX; PYST2

Cat.No. Product Name Price
SHH281913 shRNA set against Human DUSP7 (NM_001947.3) Inquiry
SHH281917 shRNA set against Mouse DUSP7 (NM_153459.4) Inquiry
SHW016049 shRNA set against Danio rerio DUSP7 (NM_199774) Inquiry
Cat.No. Product Name Price
CDFH005497 Human DUSP7 cDNA Clone(NM_001947.3) Inquiry
CDFL003880 Mouse Dusp7 cDNA Clone(NM_153459.4) Inquiry
MiUTR3H-05291 DUSP7 miRNA 3'UTR clone Inquiry
CDCB177524 Danio rerio DUSP7 ORF Clone (NM_199774) Inquiry
CDCB190920 Rabbit DUSP7 ORF clone (XM_008260751.1) Inquiry
CDCR057848 Human DUSP7 ORF clone (NM_001947.3) Inquiry
CDCR270360 Mouse Dusp7 ORF Clone(NM_153459.4) Inquiry
CDCS410532 Human DUSP7 ORF Clone (BC019107) Inquiry
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