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DUSP2


Official Full Name
dual specificity phosphatase 2
Organism
Homo sapiens
Gene ID
1844
Background
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus. [provided by RefSeq, Jul 2008]
Synonyms
PAC1; PAC-1

Cat.No. Product Name Price
SHW006784 shRNA set against Danio rerio DUSP2 (NM_001003451) Inquiry
SHH019019 shRNA set against Rat Dusp2(NM_001012089.1) Inquiry
SHH019037 shRNA set against Mouse Dusp2(NM_010090.2) Inquiry
SHH281785 shRNA set against Mouse DUSP2 (NM_010090.2) Inquiry
SHH281789 shRNA set against Rat DUSP2 (NM_001012089.1) Inquiry
Cat.No. Product Name Price
CDFR002515 Rat Dusp2 cDNA Clone(NM_001012089.1) Inquiry
MiUTR1M-04061 DUSP2 miRNA 3'UTR clone Inquiry
MiUTR1R-01612 DUSP2 miRNA 3'UTR clone Inquiry
MiUTR3H-05618 DUSP2 miRNA 3'UTR clone Inquiry
CDCB168259 Danio rerio DUSP2 ORF Clone (NM_001003451) Inquiry
CDCB185668 Rabbit DUSP2 ORF clone (XM_008253851.1) Inquiry
CDCH386045 Human DUSP2 ORF clone(NM_004418.3) Inquiry
CDCR057770 Mouse Dusp2 ORF clone (NM_010090.2) Inquiry
CDCR369603 Rat Dusp2 ORF Clone(NM_001012089.1) Inquiry
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