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DUSP12


Official Full Name
dual specificity phosphatase 12
Organism
Homo sapiens
Gene ID
11266
Background
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. [provided by RefSeq, Jul 2008]
Synonyms
YVH1; DUSP1

Cat.No. Product Name Price
SHH281697 shRNA set against Human DUSP12 (NM_007240.1) Inquiry
SHH018551 shRNA set against Human DUSP12(NM_007240.1) Inquiry
SHH018569 shRNA set against Mouse Dusp12(NM_023173.2) Inquiry
SHH018587 shRNA set against Rat Dusp12(NM_022248.1) Inquiry
SHH281701 shRNA set against Mouse DUSP12 (NM_023173.2) Inquiry
SHH281705 shRNA set against Rat DUSP12 (NM_022248.1) Inquiry
SHW004306 shRNA set against Chicken DUSP12 (NM_001278099) Inquiry
SHW008966 shRNA set against Danio rerio DUSP12 (NM_001025177) Inquiry
Cat.No. Product Name Price
CDFH005480 Human DUSP12 cDNA Clone(NM_007240.1) Inquiry
CDFR011931 Rat Dusp12 cDNA Clone(NM_022248.1) Inquiry
MiUTR1H-03027 DUSP12 miRNA 3'UTR clone Inquiry
MiUTR1M-04054 DUSP12 miRNA 3'UTR clone Inquiry
MiUTR1R-01609 DUSP12 miRNA 3'UTR clone Inquiry
CDCB165781 Chicken DUSP12 ORF Clone (NM_001278099) Inquiry
CDCB170441 Danio rerio DUSP12 ORF Clone (NM_001025177) Inquiry
CDCB182608 Rabbit DUSP12 ORF clone (XM_008264166.1) Inquiry
CDCR057702 Human DUSP12 ORF clone (NM_007240.1) Inquiry
CDCR057718 Mouse Dusp12 ORF clone (NM_023173.2) Inquiry
CDCR378934 Rat Dusp12 ORF Clone(NM_022248.1) Inquiry
CDCS413131 Human DUSP12 ORF Clone (BC006286) Inquiry
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