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DUS2L

Official Full Name
dihydrouridine synthase 2
Organism
Homo sapiens
GeneID
54920
Background
This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]
Synonyms
DUS2; SMM1; DUS2L; URLC8;

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