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DUOX1


Official Full Name
dual oxidase 1
Organism
Homo sapiens
Gene ID
53905
Background
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2012]
Synonyms
LNOX1; THOX1; NOXEF1

Cat.No. Product Name Price
SHH018011 shRNA set against Mouse Duox1(NM_001099297.1) Inquiry
SHH281557 shRNA set against Human DUOX1 (NM_175940.1) Inquiry
SHH018029 shRNA set against Human DUOX1(NM_017434.3) Inquiry
SHH018047 shRNA set against Human DUOX1(NM_175940.1) Inquiry
SHH018065 shRNA set against Rat Duox1(NM_153739.1) Inquiry
SHH281561 shRNA set against Mouse DUOX1 (NM_001099297.1) Inquiry
SHH281565 shRNA set against Rat DUOX1 (NM_153739.1) Inquiry
Cat.No. Product Name Price
CDFG000741 Human DUOX1 cDNA Clone(NM_017434.3) Inquiry
CDFG010816 Human DUOX1 cDNA Clone(NM_175940.1) Inquiry
CDFR014624 Rat Duox1 cDNA Clone(NM_153739.1) Inquiry
MiUTR1H-03021 DUOX1 miRNA 3'UTR clone Inquiry
MiUTR1H-03022 DUOX1 miRNA 3'UTR clone Inquiry
MiUTR1M-04046 DUOX1 miRNA 3'UTR clone Inquiry
MiUTR1R-01604 DUOX1 miRNA 3'UTR clone Inquiry
CDCB190852 Rabbit DUOX1 ORF clone (XM_002717902.2) Inquiry
CDCR057646 Mouse Duox1 ORF clone (NM_001099297.1) Inquiry
CDCR301785 Human DUOX1 ORF Clone(NM_017434.3) Inquiry
CDCR381723 Rat Duox1 ORF Clone(NM_153739.1) Inquiry
CDCR382613 Human DUOX1 ORF Clone(NM_175940.1) Inquiry
CDCS414398 Human DUOX1 ORF Clone (BC114938) Inquiry
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