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DOK5


Official Full Name
docking protein 5
Organism
Homo sapiens
Gene ID
55816
Background
The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Synonyms
IRS6; IRS-6; C20orf180

Cat.No. Product Name Price
SHH280317 shRNA set against Human DOK5 (NM_018431.3) Inquiry
SHH280321 shRNA set against Mouse DOK5 (NM_029761.4) Inquiry
Cat.No. Product Name Price
CDFG001854 Human DOK5 cDNA Clone(NM_018431.3) Inquiry
MiUTR1H-02957 DOK5 miRNA 3'UTR clone Inquiry
CDCB189814 Rabbit DOK5 ORF clone (XM_008274150.1) Inquiry
CDCR056924 Mouse Dok5 ORF clone (NM_001163686.1) Inquiry
CDCR303751 Human DOK5 ORF Clone(NM_018431.3) Inquiry
CDCS414792 Human DOK5 ORF Clone (BC008992) Inquiry
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