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DNASE1L3

Official Full Name
deoxyribonuclease 1L3
Organism
Homo sapiens
GeneID
1776
Background
This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
Synonyms
D3; LSD; DHP2; SLEB16; DNAS1L3;

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