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DMTF1


Official Full Name
cyclin D binding myb like transcription factor 1
Organism
Homo sapiens
Gene ID
9988
Background
This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Synonyms
DMP1; DMTF; MRUL; hDMP1

Cat.No. Product Name Price
SHH008803 shRNA set against Mouse Dmtf1(NM_011806.3) Inquiry
SHH008831 shRNA set against Rat Dmtf1(NM_053693.1) Inquiry
SHH278995 shRNA set against Mouse DMTF1 (NM_011806.3) Inquiry
SHH278997 shRNA set against Rat DMTF1 (NM_053693.1) Inquiry
SHW002562 shRNA set against Chicken DMTF1 (NM_001080863) Inquiry
SHW006660 shRNA set against Danio rerio DMTF1 (NM_001002665) Inquiry
Cat.No. Product Name Price
CDCB158195 Human DMTF1 ORF clone (BC070064) Inquiry
MiUTR3H-10037 DMTF1 miRNA 3'UTR clone Inquiry
MiUTR1R-01517 DMTF1 miRNA 3'UTR clone Inquiry
MiUTR1M-03904 DMTF1 miRNA 3'UTR clone Inquiry
CDFR013402 Rat Dmtf1 cDNA Clone(NM_053693.1) Inquiry
CDFL003695 Mouse Dmtf1 cDNA Clone(NM_011806.3) Inquiry
CDFH005222 Human DMTF1 cDNA Clone(NM_001142327.1) Inquiry
CDFH005221 Human DMTF1 cDNA Clone(NM_001142326.1) Inquiry
CDFG019005 Mouse Dmtf1 cDNA Clone(NM_001110327.1) Inquiry
MiUTR3H-10039 DMTF1 miRNA 3'UTR clone Inquiry
MiUTR3H-10038 DMTF1 miRNA 3'UTR clone Inquiry
CDCR380359 Rat Dmtf1 ORF Clone(NM_053693.1) Inquiry
CDCR351184 Human DMTF1 ORF Clone(NM_001142327.1) Inquiry
CDCR251343 Mouse Dmtf1 ORF Clone(NM_011806.3) Inquiry
CDCR056144 Mouse Dmtf1 ORF clone (NM_001110327.1) Inquiry
CDCR056140 Human DMTF1 ORF clone (NM_001142326.1) Inquiry
CDCB184205 Rabbit DMTF1 ORF clone (XM_008261799.1) Inquiry
CDCB168135 Danio rerio DMTF1 ORF Clone (NM_001002665) Inquiry
CDCB164037 Chicken DMTF1 ORF Clone (NM_001080863) Inquiry
CDCS408254 Human DMTF1 ORF Clone (BC070064) Inquiry
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