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DLG3

Official Full Name
discs large MAGUK scaffold protein 3
Organism
Homo sapiens
GeneID
1741
Background
This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]
Synonyms
MRX; XLMR; MRX90; NEDLG; SAP102; XLID90; PPP1R82;

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