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DHPS

Official Full Name
deoxyhypusine synthase
Background
This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms
DHPS; deoxyhypusine synthase; MIG13; migration inducing gene 13; DHS; DHYS_HUMAN; DS; migration-inducing gene 13; DS, DHS, MIG13, DHPS; zgc:56018; zgc:77325; wu:fb52g04; wu:fj48f12; zgc:111900

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